Table 1:

Clinical characteristics of Patients with IDH1 Mutant and IDH Wild Type Intrahepatic Cholangiocarcinoma, small duct type

Variable	Wild type IDH	Mutant IDH1	p-value
	N = 72	N = 29
Age (Median, IQR)	67 (58, 73)	73 (65, 78)	0.052
Sex			0.7
F	42 (58%)	15 (52%)
M	30 (42%)	14 (48%)
Ethnicity			0.3
Asian	6 (8.3%)	2 (6.9%)
Black	6 (8.3%)	0 (0%)
White	60 (83%)	27 (93%)
Autoimmune disease	3 (4.2%)	6 (21%)	0.016
Chronic viral hepatitis B/C	9 (19%)	3 (14%)	0.7
Unknown	25	8
Smoking	29 (40%)	14 (50%)	0.5
Unknown	0	1
Clinical cirrhosis	7 (9.7%)	1 (3.6%)	0.4
Unknown	0	1
Frequent alcohol	3 (4.2%)	3 (11%)	0.3
Unknown	0	1
Steatosis	4 (5.6%)	3 (11%)	0.4
Unknown	0	2
Neoadjuvant chemotherapy (systemic or intrahepatic)			>0.9
Any chemo	7 (9.7%)	3 (11%)
No chemo	65 (90%)	25 (89%)
Unknown	0	1