Table 3:
Baseline characteristics, laboratory values, and liver volume measurements stratified by outcomes during follow up.
| Variables | Alive (N=341) |
Transplanted (N=112) |
Dead (N=131) |
p-value |
|---|---|---|---|---|
| Age (Yrs) | 55.8±10.1 | 53.4±9.9* | 58.4±9.6* | 0.0004 |
| Gender (Men, n %) | 206 (61%) | 74 (66%) | 78 (59%) | 0.53 |
| Race (Whites, n %) | 301 (89%) | 99 (88%) | 119 (90%) | 0.67 |
| Body weight (Kg) | 87.6±20.8 | 88.4±19.9 | 85.2±24.2 | 0.4511 |
| Height (cm) | 170.5±13.5 | 172.5±13.9 | 170.3±10.2 | 0.3052 |
| Body mass index (kg/m2) | 30.6±12.8 | 30.1±8.5 | 29.3±7.4 | 0.4921 |
| White blood cell counts (×103/mm3) | 5.8±3.0 | 5.2±4.1 | 6.4±3.4 | 0.0333 |
| Hemoglobin (g/dl) | 12.6±3.0 | 12.1±2.3 | 12.7±11.0 | 0.6081 |
| Platelet counts (×103/mm3) | 123.0±86.3 | 88.7±44.2 | 107.6±76.0 | 0.0002 |
| Blood urea nitrogen (mg/dl) | 14.1±10.4 | 14.1±7.5 | 17.6±18.5 | 0.0197 |
| Creatinine (mg/dl) | 1.2±1.5 | 1.0±0.9 | 1.3±2.0 | 0.3962 |
| Total bilirubin (mg/dl) | 2.2±2.9 | 2.6±2.0* | 3.7±4.7*,$ | <0.0001 |
| Alanine aminotransferase (ALT, U/L) | 55.6±104.9 | 53.9±63.4 | 48.7±35.7 | 0.7485 |
| Aspartate aminotransferase (AST, U/L) | 76.4±131.9 | 78.8±71.9 | 79.1±49.4 | 0.9608 |
| Alkaline phosphatase (ALP, U/L) | 131.1±138.7 | 142.6±92.3 | 139.1±140.9 | 0.6780 |
| Albumin (g/dl) | 3.2±0.6 | 3.0±0.7* | 2.8±0.6*,$ | <0.0001 |
| Total protein (g/dl) | 7.2±4.1 | 6.9±0.9 | 6.9±1.0 | 0.5521 |
| International normalized ratio (INR) | 1.4±1.0 | 3.0±15.5 | 1.6±0.5 | 0.1272 |
| MELD scores | 10.0±6.3 | 12.0±7.2* | 13.6±8.6*,$ | <0.0001 |
| Liver volume without body weight adjustment | ||||
| Total liver volume (TLV, cm3) | 1740.1±574.4 | 1529.7±506.8* | 1486.6±495.6*,$ | <0.0001 |
| Functional liver volume (FLV, cm3) | 1691.7±558.0 | 1487.2±488.8* | 1444.3±487.5*,$ | <0.0001 |
| Segment 1 volume (cm3) | 44.8±48.0 | 41.6±42.4 | 48.5±49.2 | 0.5375 |
| Segment 2 volume (cm3) | 256.8±147.8 | 277.9±334.9 | 242.8±137.0 | 0.3392 |
| Segment 3 volume (cm3) | 198.5±152.7 | 161.5±104.4* | 161.7±114.6* | 0.0062 |
| Segment 4 volume (cm3) | 259.2±147.8 | 234.6±126.0 | 228.8±177.3 | 0.0911 |
| Segment 5 volume (cm3) | 249.1±154.8 | 206.2±117.5* | 200.7±102.7*,$ | 0.0005 |
| Segment 6 volume (cm3) | 175.7±145.8 | 147.4±97.1 | 149.0±135.0 | 0.0563 |
| Segment 7 volume (cm3) | 269.2±154.9 | 226.7±104.1* | 226.5±106.9* | 0.0003 |
| Segment 8 volume (cm3) | 247.0±105.5 | 216.0±100.7* | 207.6±97.4*,$ | 0.0002 |
| Liver volume with body weight adjustment | ||||
| Total volume:body weight (cm3:kg) | 20.6±8.9 | 17.9±7.4* | 18.4±7.0*,$ | 0.0016 |
| functional volume:body weight (cm3:kg) | 20.0±8.7 | 17.4±7.1* | 17.8±6.8* | 0.0016 |
| Segment 1:BW (cm3/kg) | 0.5±0.6 | 0.5±0.5 | 0.6±0.7 | 0.1459 |
| Segment 2:BW (cm3/kg) | 3.1±1.8 | 3.2±3.0 | 3.0±1.9 | 0.8138 |
| Segment 3:BW (cm3/kg) | 2.4±2.1 | 1.9±1.3* | 2.0±1.4*,$ | 0.0092 |
| Segment 4:BW (cm3/kg) | 3.1±2.1 | 2.7±1.7 | 2.8±2.0 | 0.1347 |
| Segment 5:BW (cm3/kg) | 2.9±1.9 | 2.4±1.5 | 2.4±1.2 | 0.0034 |
| Segment 6:BW (cm3/kg) | 2.0±1.5 | 1.7±1.3 | 1.9±1.9 | 0.2052 |
| Segment 7:BW (cm3/kg) | 3.2±1.7 | 2.7±1.4* | 2.8±1.4* | 0.0050 |
| Segment 8:BW (cm3/kg) | 2.9±1.3 | 2.5±1.3* | 2.5±1.2* | 0.0028 |
*
significant compared to those who were alive,
$
significant compared to those who were transplanted