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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Hum Mutat. 2019 Aug 7;40(9):1579–1592. doi: 10.1002/humu.23826

Table 3.

Overview of two types of baseline machine learning models compared in this study as well as our model weakly supervised model.

Model Target Label Learning Type Ordered Classes Scaled Classes
Multi-class Logistic Regression Pathogenicity Class Classification
Cumulative Logit Model Pathogenicity Class Classification
Weakly Supervised Regression Pathogenicity Probability Regression