Table 1.

Clinical, laboratory and radiographic assessments according to the BARFOT protocol

Assessment	Measurement variable	Measurement method
Disease activity	Patient's global assessment (PatGA)	VAS (range 0–100 mm, best to worse)
	Patient’s assessment of pain	VAS (range 0–100 mm, best to worse)
	Physician's global assessment	Five-grade Likert scale
	Number of tender joints	Calculated on 28 joints
	Number of swollen joints	Calculated on 28 joints
	Acute phase response	Erythrocyte sedimentation rate (ESR)
	Acute phase response	C-reactive protein (CRP)
	Disease activity score, DAS28	VAS PatGA, swollen and tender joint count, ESR
Disease remission	DAS28<2.6
Function	Disability	Swedish version of the Health Assessment Questionnaire (HAQ)
Physical impairment	The Signals of Functional Impairment (SOFI)
Joint damage	Radiographs of the hands and feet	Van der Heijde modification of the Sharp score (SHS), with total, erosion and joint space narrowing scores.
Larsen score
Biomarkers	Autoantibodies	Rheumatoid factor (RF) test anti-CCP2 test

Abbreviation: DAS28, 28-joint disease activity score.