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AKR1D1 expression in obese patients. In male (n = 7) and female (n = 27) obese patients, AKR1D1 mRNA expression decreased with more advanced fibrosis (a-b), steatosis percentage (c) and higher NAFLD Activity Score (NAS) (d). In addition, mRNA expression of AKR1D1 was reduced in patients with T2DM (e). qPCR data were normalised to 18SrRNA, TBP and ACTB. Data are presented as mean ± se, performed in triplicate, *p < 0.05, **p < 0.01.
