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. 2019 Sep 13;2:336. doi: 10.1038/s42003-019-0574-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Intermediary metabolism is suppressed in the fasted state. Schematic illustrating the regulation and endpoint of major metabolic pathways in adipose (A), liver (L), and muscle (M). Log₂ fold change is indicated next to each gene; red numbers indicate significantly decreased expression in hibernation, whereas blue indicates significantly increased expression in hibernation (N = 6 animals, FDR < 0.05; Supplementary Data 2)