Table 1.
Univariate analysis of prognostic parameters for PFS in medulloblastoma patients (n = 116).
| Parameters | No. of cases | 5-year PFS (%) | P-value |
|---|---|---|---|
| Sex | |||
| Male | 75 (64.7%) | 48 | 0.801 |
| Female | 41 (35.3%) | 49.2 | |
| Age | |||
| Children | 93 (80.2%) | 43.3 | 0.109 |
| Adults | 23 (19.8%) | 70.6 | |
| PreKPS | |||
| <80 | 37 (31.9%) | 38.2 | 0.387 |
| ≥80 | 79 (68.1%) | 52.1 | |
| Location | |||
| Midline | 88 (75.9%) | 39.1 | 0.048 |
| Lateral | 28 (24.1%) | 70.4 | |
| Extent of resection | |||
| Gross Total | 62 (53.4%) | 71.0 | <0.001 |
| Subtotal | 54 (46.6%) | 24.4 | |
| RT | |||
| Yes | 93 (80.2%) | 52.4 | 0.003 |
| No | 23 (19.8%) | 31.5 | |
| CHT | |||
| Yes | 64 (55.2%) | 46.9 | 0.564 |
| No | 52 (44.8%) | 51.8 | |
| NLR | |||
| NLR ≤ 4.94 | 102 (87.9%) | 51.3 | 0.004 |
| NLR > 4.94 | 14 (12.1%) | 28.6 | |
| PLR | |||
| PLR ≤ 142.31 | 72 (62.1%) | 55.0 | 0.028 |
| PLR > 142.31 | 44 (37.9%) | 38.5 | |
| MLR | |||
| MLR ≤ 0.33 | 102 (87.9%) | 49.8 | 0.157 |
| MLR > 0.33 | 14 (12.1%) | 39.2 | |
| MPV | |||
| MPV ≤ 8.80 | 88 (75.9%) | 44.6 | 0.303 |
| MPV > 8.80 | 28 (24.1%) | 60.0 | |
| PDW | |||
| PDW ≤ 15.90 | 43 (37.1%) | 37.8 | 0.096 |
| PDW > 15.90 | 73 (62.9%) | 56.0 | |
| AGR | |||
| AGR ≤ 1.59 | 22 (19.0%) | 32.9 | 0.22 |
| AGR > 1.59 | 94 (81.0%) | 52.7 | |
PreKPS: preoperative karnofsky performance status scale.
RT: postoperative primary radiotherapy.
CHT: postoperative primary chemotherapy.
NLR: neutrophil-to-lymphocyte ratio.
PLR: platelet-to-lymphocyte ratio.
MLR: monocyte-to-lymphocyte ratio.
MPV: mean platelet volume.
PDW: platelet distribution width.
AGR: preoperative albumin-to-globulin ratio.