Fig. 2.

Time course of muscle changes. Time course of changes in muscle maximum uncoupled respiration (CON n = 14, OB n = 45) (a), citrate synthase activity (CSA) (CON n = 13, OB n = 45) (b), electron transport chain complex II succinate dehydrogenase complex iron sulfur subunit B protein content (CON n = 10, OB n = 15) (c), respiratory control ratio (RCR) (CON n = 13, OB n = 43) (d), leak control ratio (LCR) (CON n = 13, OB n = 44) (e) and serum antioxidant capacity (CON n = 6, OB n = 28) (f) in obese (empty circles) and nonobese humans at baseline (black circles). Mean ± SEM, *p < 0.05 vs OB at baseline (0 w) using CPM for repeated measures analysis, #p < 0.05 vs CON using unpaired two-tailed t-test. CON nonobese humans, OB obese participants