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Time course of (A) the dynamic weight bearing, (B) the static weight bearing, (C) the mechanical sensitivity of the injected left hind paw, and (D) the body weight development in naïve control rats and rats before and after induction of monoarthritis by injecting MIA into the ankle or knee joint. Bonferroni’s test subsequent to 2-way RM ANOVA: * = p < 0.05, ** = p < 0.01, *** = p < 0.001. Data shown as mean ± 95% CI, n = 9 per group.
