Table 2. RRs and 95% CIs for the association between ALB and risk of the major epithelial ovarian cancer subtypes.
Author (year) | Exposure (ALB) | Histologic subtypes of epithelial ovarian cancer | |||||
---|---|---|---|---|---|---|---|
Serous | Mucinous | Endometrioid | Clear cell | ||||
Gaitskell (2018) | ≥30/<25 | 0.94 (0.85–1.04) | 0.91 (0.74–1.12) | 0.96 (0.74–1.24) | 0.78 (0.56–1.08) | ||
Titus-Ernstoff (2001) | ≥30/<30 | Borderline | Invasive | 1.10 (0.60–2.00) | |||
0.80 (0.40–1.60) | 1.00 (0.70–1.50) | ||||||
Soegaard (2007) | ≥30/<25 | 0.64 (0.39–1.04) | 0.74 (0.25–2.18) | 0.71 (0.27–1.89) | |||
Sköld (2018) | ≥40/<25 | 0.58 (0.48–0.70) | 0.93 (0.65–1.34) | 0.39 (0.24–0.65) | 1.01 (0.57–1.79) | ||
Tung (2003) | >34/<28 | Borderline | Invasive | Borderline | Invasive | 1.10 (0.40–2.70) | 0.80 (0.30–2.00) |
0.50 (0.20–1.30) | 1.20 (0.70–1.90) | 0.60 (0.20–1.50) | 0.70 (0.20–2.20) | ||||
Pooled RR (95% CI) | The highest versus the lowest stratification | 0.80 (0.62–1.03) I2 = 75.70%, P<0.001 |
0.91 (0.77–1.07) I2 = 0.00%, P=0.927 |
0.72 (0.42–1.24) I2 = 71.10%, P=0.016 |
0.83 (0.63–1.09) I2 = 0.00%, P=0.743 |