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. 2019 Sep 14;25:44. doi: 10.1186/s10020-019-0111-4

Fig. 4.

Fig. 4

In vivo validation of the inductive effect of R116C mutation on pancreatic carcinogenesis and tumor development. a. Tumor-bearing mice, low differentiated adenocarcinoma (400×); b. Gross changes in the pancreas of human PRSS1_R116C transgenic mice. c. Gross changes in the pancreas of the transgenic mouse model