Table 2.
Mean value lymphocyte phenotype, analytical (CVA), intra-individual (CVI), and inter-individual (CVG) components of variation for five lymphocyte phenotypes
| Biomarker | Weighted Mean (%) | CV A (%) | Intra-subject variation CV I (%) |
Inter-subject variation CVG (%) | ||||
|---|---|---|---|---|---|---|---|---|
| Phenotype | Male | Female | Both | Male | Female | Both | ||
| CD3 (T cells) | 73 | 1.0 | 3.0 | 4.1 | 3.6 | 8.3 | 13.6 | 10.8 |
| CD4 | 46 | 3.2 | 6.8 | 5.6 | 6.1 | 10.5 | 20.9 | 20.7 |
| CD8 | 25 | 2.4 | 6.9 | 5.7 | 6.7 | 20.3 | 43.6 | 35.5 |
| CD19 (B cells) | 12 | 4.1 | 22.0 | 12.6 | 17.4 | 27.4 | 37.0 | 31.9 |
| CD56/16 (NK cells) | 13 | 5.8 | 21.4 | 24.9 | 23.0 | 23.4 | 50.9 | 37.1 |
CVA is analytical variation (mean CV of daily QC run for 20 days) expressed as a %CV