. Author manuscript; available in PMC: 2019 Sep 14.

Published in final edited form as: J Thromb Thrombolysis. 2017 Aug;44(2):145–153. doi: 10.1007/s11239-017-1516-y

Table 4:

Rate of Change of Biomarkers over each Time Period

Biomarkers	Slope (Rate of change per month)	Estimate	95% Confidence Limit	P value for different slopes	P value for interaction with treatment
Platelet Count	Slope 1: Baseline to 1M			<.0001	<.0001
	Ticagrelor	17.4040	(15.316, 19.492)
	Clopidogrel	8.9605	(6.8754, 11.046)
	Slope 2: 1Mth to 6M				0.8663
	Ticagrelor	−1.5535	(−1.971, −1.136)
	Clopidogrel	−1.5028	(−1.920, −1.086)
CD40 Ligand	Slope 1: Baseline to 1M	−0.04948	(−.1118, 0.0128)	0.1828	0.7730
CD40 Ligand	Slope 2: 1Mth to 6M	−0.00233	(−.0148, 0.0101)		0.5342
P-Selectin	Slope 1: Baseline to 1M	−4.9842	(−6.039, −3.929)	<.0001	0.4251
P-Selectin	Slope 2: 1Mth to 6M	0.3676	(0.1566, 0.5785)		0.2076