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. Author manuscript; available in PMC: 2020 Sep 11.
Published in final edited form as: J Am Chem Soc. 2019 Aug 29;141(36):14005–14020. doi: 10.1021/jacs.9b06222

Figure 2.

Figure 2.

(a) Chemical structures of MOCs 18–20; (b) MOC 18–20-related anticancer therapy. Top, NIRFI of U87MG tumor-bearing nude mice following injection of MNPs. Middle, PET image of U87MG tumor-bearing nude mice at 2, 4, 6, 12, 24, and 48 h post injection of 64Cu@MNPs. Bottom, in vivo T1-weighted axial MRI images (7T) of the mice before and after injection of Mn@MNPs. Chemical structures of (c) MOC 21, (d) MOCs 22, 23, (e) MOC 24, (f) MOC 25, (g) MOCs 26–28, (h) MOCs 29–32, (i) MOCs 33, 34, (j) MOCs 35, 36, and (k) MOCs 37–39. Adapted with permission from refs 27–28, 30, 51–52, 60, 62 and 64–65. 2015, 2016 and 2017 the Royal Society of Chemistry, 2014 and 2016 National Academy of Sciences (USA), 2014 Wiley-VCH, 2016 Elsevier. 2018 Nature Publishing Group.