Table 2.

Spearman rank correlation coefficients for associations between functional impairment scores and brain volume measures in patients with Wilson’s disease

	NBV	BPF	vCSF	GM	WM	PGM	DGM
UWDRS_FI	− 0.388	− 0.622	0.634	− 0.236	− 0.399	− 0.325	− 0.458
	p = 0.006	p < 0.0001	p < 0.0001	p = 0.110	p = 0.005	p = 0.024	p = 0.001

UWDRS_FI Unified Wilson’s Disease Rating Scale—functional impairment, NBV normalized brain volume, BPF brain parenchymal fraction, vCSF ventricular cerebrospinal fluid, GM gray matter, WM white matter, PGM peripheral gray matter, DGM deep gray matter