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Metanuclear changes for cytotoxicity evaluation (pyknosis, karyorrhexis, and karyolysis) in mouse hepatocytes treated with sakuranetin. p > 0.05. Data represent mean ± SEM from 5 mice per group.
| Groups | Metanuclear changes | ||
|---|---|---|---|
| Pyknosis | Karyorrhexis | Karyolysis | |
| SAL | 9 ± 6.7 | 22.5 ± 6.5 | 199 ± 8.5 |
| OVA | 16 + 2 ± 6.7 | 29.2 ± 13.5 | 196.5 ± 28.7 |
| SK | 17 ± 8.8 | 25.5 ± 9.3 | 211 ± 27 |
