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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Neuropharmacology. 2019 Jul 26;158:107727. doi: 10.1016/j.neuropharm.2019.107727

Figure 4. Effects of r-Slit2 on neurological function at 4 weeks post HIE.

Figure 4.

(A–B) Representative pictures of Nissl’s stain for the brain slices showed tissue loss which was significantly reduced on treatment with r-Slit2 as compared to vehicle. (C–D) Rh-Slit2 group showed a significant improvement in neurological function as shown by water-maze, where memory and learning was evaluated. (Data represent +/− SD; *p<0.05 versus sham, # versus vehicle; n=6/group using one-way or two way ANOVA followed by Tukey multiple-comparison post hoc analysis). (E–F) Rh-Slit2 showed to improve motor deficits as seen from rota rod and foot fault tests. (Data represent +/− SD; *p<0.05 versus sham, # versus vehicle; n=6/group using one-way or two-way ANOVA followed by Tukey multiple-comparison post hoc analysis).