Table 1.

Effect of 19-HETE Analogs (1 μM) on 20-HETE (1 μM) Induced Vascular Sensitization to Phenylephrine.^a

Analog Number	Structure	Fold Change from 20-HETEb	Analog Number	Structure	Fold Change from 20-HETEb
4		−0.68	15		−0.79
5		−0.85	16		−2.19
6		−5.69	17		−2.56
7		−5.45	18		−2.17
8		0.16	19		−1.13
9		0.50	20		0.58
10		−3.46	21		−1.16
11		−4.67	22		−0.68
12		−0.59	23		−0.74
13		−2.03	24		−0.78
14		−0.66

^an = 3-5.

^bNegative values indicate antagonism of 20-HETE sensitization and positive values indicate enhancement of 20-HETE activity.