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iPSC-derived cardiomyocytes exhibit inter-individual variability in treatment-related points of departure (PODs) for phenotypes beats per minute, decay/rise ratio, total cells, and peak spacing CV. Box plots show median and interquartile range across 134 chemicals, and are ordered by the median POD. Donors more sensitive to chemical-induced effects are indicated by lower median POD across chemicals, and donors more resistant to effects are indicated by higher median POD.
