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. Author manuscript; available in PMC: 2020 Jul 4.
Published in final edited form as: Adv Drug Deliv Rev. 2019 Jul 4;144:35–56. doi: 10.1016/j.addr.2019.07.002

Figure 2.

Figure 2.

The therapeutic window of radiation therapy is a balance between tumor control and normal tissue complications. Addition of radiosensitizers reduce the dose of radiation required for the same tumor control probability. Addition of radio-protective drugs increase the dose of radiation required for the same probability of normal tissue complications. Together, radiosensitizers and radio-protective drugs can enhance the therapeutic window of RT. Reprinted with permission from [19].