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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Neuropharmacology. 2019 Apr 8;158:107597. doi: 10.1016/j.neuropharm.2019.04.003

Figure 2.

Figure 2.

Phase I metabolic stability of R-VK4-40 in rat liver microsomes fortified with NADPH. R-VK4-40 was stable in rat liver microsomes with 86 ± 2 % intact remaining following 60 min incubation. Control experiments without cofactors were conducted in parallel with >95% compound remained at 60 min.