Table 1.
Baseline characteristics of study population stratified by stress GLS above and below the median (−19%).
| CHARACTERISTICS | Total | Stress GLS <median |
Stress GLS ≥median |
P Value |
|---|---|---|---|---|
| CLINICAL VARIABLES | ||||
| Age (±SD), years | 58.4 (±13.1) | 58.1 (±13.2) | 58.7 (±13.1) | 0.604 |
| Male % | 45.3 | 35.0 | 55.4 | <0.001 |
| BMI (±SD), kg/m2 | 30.5 (±6.2) | 30.9 (±6.2) | 30.1 (±6.1) | 0.132 |
| Diabetes % | 34.6 | 28.7 | 40.3 | 0.006 |
| Hyperlipidemia % | 55.1 | 51.6 | 58.5 | 0.114 |
| Hypertension % | 75.6 | 69.7 | 81.4 | 0.002 |
| Smoking % | 17.5 | 14.6 | 20.5 | 0.076 |
| History of MI % | 15.6 | 8.3 | 22.9 | <0.001 |
| CMR VARIABLES | ||||
| Baseline Heart Rate (±SD), beats/min | 65.0 (±12.4) | 63.3 (±11.6) | 66.6 (±13.0) | 0.007 |
| LVEDV index (±SD), ml/m2 | 64.1 (±20.7) | 62.8 (±15.5) | 65.3 (±24.8) | 0.168 |
| LVESV index (±SD), ml/m2 | 24.3 (±17.8) | 20.2 (±11.0) | 28.3 (±21.9) | <0.001 |
| LGE present % | 16.8 | 5.5 | 27.9 | <0.001 |
| LGE size‡ (IQR) | 0 (0,0) | 0 (0,0) | 0 (0,1) | <0.001 |
| Resting GLS (IQR), % | −17(−19,−15) | −19(−20,−18) | −15(−17,−12) | <0.001 |
| Ischemia present % | 10.5 | 2.4 | 18.6 | <0.001 |
| Ischemia extent‡ (IQR) | 0 (0,0) | 0 (0,0) | 0 (0,0) | <0.001 |
| LVEF (±SD), % | 59.7 (±11.9) | 63.1 (±8.4) | 56.4 (±13.8) | <0.001 |
BMI=Body Mass Index, GLS=Global Longitudinal Strain, IQR=Interquartile Range, LGE=Late Gadolinium Enhancement, LVEDV =Left Ventricular End Diastolic Volume Index, LVEF=Left Ventricular Ejection Fraction, LVESV =Left Ventricular End Systolic Volume Index, MI=Myocardial Infarction, SD=standard deviation.
‡
expressed as percent LV.