Table 3 -.
Hazard Ratios for all-cause and cause-specific mortality by CAC score group
| A. CAC 0 as reference group | ||||
| Model 1 - Unadjusted HRs | ||||
| Agatston score | Cause of Mortality, HR (95% CI) | |||
| CVD | CHD | Cancer | All-cause | |
| 0 | REF | REF | REF | REF |
| 1–399 | 3.49 (2.85 – 4.27) | 4.14 (3.05 – 5.63) | 1.96 (1.70 – 2.26) | 2.50 (2.28 – 2.75) |
| 400–999 | 10.85 (8.63 – 13.64) | 14.86 (10.64 – 20.74) | 3.52 (2.88 – 4.30) | 6.07 (5.39 – 6.83) |
| ≥ 1000 | 24.23 (19.49 – 30.12) | 36.26 (26.44 – 49.73) | 5.87 (4.80 – 7.18) | 11.64 (10.38 – 13.05) |
| Model 2 - Fully adjusted HRs | ||||
| Agatston score | Cause of Mortality, HR (95% CI) | |||
| CVD | CHD | Cancer | All-cause | |
| 0 | REF | REF | REF | REF |
| 1–399 | 1.77 (1.43 – 2.18) | 1.99 (1.45 – 2.74) | 1.09 (0.94 – 1.27) | 1.37 (1.24 – 1.52) |
| 400–999 | 3.09 (2.41 – 3.97) | 3.90 (2.72 – 5.59) | 1.19 (0.95 – 1.48) | 1.98 (1.73 – 2.25) |
| ≥ 1000 | 5.04 (3.92 – 6.48) | 6.79 (4.74 – 9.73) | 1.55 (1.23 – 1.95) | 2.89 (2.53 – 3.31) |
| B. CAC 400–999 as reference group | ||||
| Model 1 - Unadjusted HRs | ||||
| Agatston score | Cause of Mortality, HR (95% CI) | |||
| CVD | CHD | Cancer | All-cause | |
| 400–999 | REF | REF | REF | REF |
| ≥ 1000 | 2.23 (1.84 – 2.70) | 2.43 (1.90 – 3.11) | 1.65 (1.31 – 2.09) | 1.91 (1.69 – 2.15) |
| ≥ 1000 | 1.71 (1.41 – 2.08) | 1.84 (1.43 – 2.36) | 1.36 (1.07 – 1.73) | 1.51 (1.33 – 1.70) |
| Model 2 - Fully adjusted HRs | ||||
| Agatston score | Cause of Mortality, HR (95% CI) | |||
| CVD | CHD | Cancer | All-cause | |
| 400–999 | REF | REF | REF | REF |
| ≥ 1000 | 1.71 (1.41 – 2.08) | 1.84 (1.43 – 2.36) | 1.36 (1.07 – 1.73) | 1.51 (1.33 – 1.70) |
*
Adjusted on age, sex, hypertension, dyslipidemia, smoking, diabetes, and family history of CHD