Table 1.
Previously reported cases of malignant struma ovarii with follicular carcinoma.
| # | First author | Year | Age | Extraovarian spread | Treatment of extraovarian disease | Prognosis and follow-up |
|---|---|---|---|---|---|---|
| 1 | De Graaff | 1983 | 72 | Peritoneal dissemination | Omentectomy | NED, 3 yrs |
| 2 | Willemse | 1987 | 36 | Peritoneal dissemination | RAI | Rec, 4 mo |
| 3 | O'Connell | 1990 | 35 | No | None | NED |
| 4 | Zakhem C1 | 1990 | 52 | No | None | NED, 1.7 yrs |
| 5 | Zakhem C2 | 1990 | 30 | No | None | NED, 2.7 yrs |
| 6 | Kragel | 1991 | 37 | Peritoneal dissemination | None | NED, 5 yrs |
| 7 | Thomas C1 | 1992 | 17 | Peritoneal dissemination | RAI | NED, 2 yrs |
| 8 | Thomas C2 | 1992 | 35 | Peritoneal dissemination | Omentectomy | NA |
| 9 | Ito | 1992 | 36 | Bone metastasis | Chemotherapy | NED, 1 mo |
| 10 | Balasch | 1993 | 36 | Peritoneal dissemination | RAI to be considered | NA |
| 11 | Ayhan | 1993 | 66 | Peritoneal dissemination | Omentectomy | AWD, 8 yrs |
| 12 | Tokuda | 1993 | 25 | Cranial metastasis | Resection | NED |
| 13 | Karseladze | 1994 | 49 | Peritoneal dissemination | Chemotherapy | NED, 16.3 yrs |
| 14 | Piana | 1994 | 26 | No | None | NED 1 yr |
| 15 | Brenner | 1996 | 49 | Urinary bladder metastsis | RAI | NED, 3.2 yrs |
| 16 | Tennvall C1 | 1997 | 50 | Peritoneal dissemination | Omentectomy, RAI | NED, 6 yrs |
| 17 | Tennvall C2 | 1997 | 43 | Peritoneal dissemination | None | Died(GBC), 4 mo |
| 18 | Mango | 1997 | 47 | Pelvic bone metastasis | RAI | AWD, 4 mo |
| 19 | Barrande | 1997 | 31 | No | RAI | NED, 6 mo |
| 20 | Bhansali | 1999 | 47 | No | Radiation | NED, 4 yrs |
| 21 | Takeuchi C1 | 2000 | 43 | Peritoneal dissemination | Omentectomy | NED, 7 yrs |
| 22 | Takeuchi C2 | 2000 | 70 | Peritoneal dissemination | Omentectomy, PLND | NED, 2 yrs |
| 23 | Rotman-Pikielny | 2000 | 46 | Liver metastasis | RAI | AWD, 6 mo |
| 24 | Konez | 2000 | 45 | Liver metastasis | RAI | NA |
| 25 | Chan | 2001 | 27 | Bone metastasis | RAI | AWD, 8 mo |
| 26 | Checrallah | 2001 | 38 | Lung and bone metastasis | RAI | AWD, 6 yrs |
| 27 | DeSimone | 2003 | 32 | No | RAI | NED, 1.2 yrs |
| 28 | Kdous | 2003 | 45 | No | None | NED, 1 yr |
| 29 | Brogsitter | 2004 | 50 | Peritoneal dissemination | RAI | NED, 6 mo |
| 30 | Ihalagama | 2004 | 27 | Pritoneal cyology positive | RAI | NED 1.5 yrs |
| 31 | Garcia | 2005 | 22 | Invasion to adjucent tissue | Resection | NED, 6 yrs |
| 32 | McDougall | 2006 | 17 | Liver and bone metastasis | RAI | AWD, 4 yrs |
| 33 | Zekri | 2006 | 26 | Lung and bone metastasis | RAI | AWD, 15 yrs |
| 34 | Roth, C1 | 2008 | 32 | Peritoneal dissemination | RAI | Rec, 26 yrs |
| 35 | Roth, C2 | 2008 | 49 | Peritoneal dissemination | Chemotherapy | NED, 16.3 yrs |
| 36 | Roth, C3 | 2008 | 50 | Peritoneal dissemination | Resection & RAI | NED, 6 yrs |
| 37 | Roth, C4 | 2008 | 70 | Peritoneal dissemination | RAI | DOD, 3 yrs |
| 38 | Prasad | 2008 | 40 | Pelvic mass | Resection & RAI | NED, 4 yrs |
| 39 | Kim | 2009 | 49 | Peritoneal dissemination | Omentectomy | NA |
| 40 | Michels | 2010 | 41 | Peritoneal dissemination | RAI | AWD, 3 mo |
| 41 | Selvaggi | 2012 | 50 | Peritoneal dissemination | Omentectomy | NED, 1 yr |
| 42 | Shirimali, C1 | 2012 | 52 | Vaginal vault mass | RAI | NA |
| 43 | Shirimali, C2 | 2012 | 59 | Peritoneal dissemination | RAI | NA |
| 44 | Shirimali, C3 | 2012 | 53 | Peritoneal dissemination | RAI | NA |
| 45 | Carey | 2014 | 70 | Peritoneal dissemination | RAI | NA |
| 46 | Ukita | 2014 | 45 | Lung and bone metastasis | Chemotherapy | AWD, 20 yrs |
| 47 | Cong | 2015 | 38 | Lung metastasis | RAI | AWD, 3 yrs |
| 48 | Kobayashi | 2015 | 49 | Spinal metastasis | Radiation | AWD, 9 mo |
| 49 | Ranade | 2015 | 55 | Peritoneal dissemination | RAI | AWD, 3 mo |
| 50 | Park | 2015 | 35 | Peritoneal dissemination | RAI | NED, 25 mo |
| 51 | Anagnostou | 2016 | 64 | Peritoneal dissemination | Omentectomy | NED, 4 yrs |
| 52 | Riggs | 2018 | 32 | Peritoneal dissemination | Laparoscopic resection | NED, 1 yr |
| 53 | Present case | 2019 | 39 | Peritoneal dissemination | Resection & RAI | AWD, 2 yrs |
Abbreviations; RAI, radioactive iodine therapy; NED, no evidence of disease; Rec, recurrence; NA, not available; AWD, alive with disease; GBC, gallbladder cancer; DOD, death of disease; C# denotes case# in the same report; PLND, pelvic lymph node dissection.
The complete list of all the reference above is provided as Supplementary material.