Figure 2.

Common Characteristics of MutLncs across Cancer Types

(A) Mutational frequency of part MutLncs in individual cancer types and pan-cancer are shown. MutLncs with higher mutation frequencies are colored red, while those with lower mutation frequencies are blue. (B) Bar chart showing the number of upregulated (red) and downregulated (blue) MutLncs across cancer types. (C) Bar chart showing the number of non-silent (red) and silent (green) MutLncs across cancer types. (D) MutLncs are listed vertically by mutation frequency in CESC. The colored bars in the map represent different mutations of lncRNAs occurring in a specific sample. Percentages of samples with mutations are specified on the right. Silent and non-silent mutations are colored green and red, respectively. The p values of MutLncs are shown on the left in a bar plot. Samples are presented as columns with the overall number of mutations plotted at the top, and the mutations classified as silent and non-silent clusters. (E) Distribution of MutLncs on different chromosomes for each cancer type (schematic of the locations of MutLncs within chromosome 17 across diverse cancer types). Two examples of MutLncs are shown on the right-hand column, denoted by a red line.