Figure 5.

Somatic Mutations with Mixed and Unmixed Effects on lncRNA Expression in Pan-Cancer

(A) Heatmap of all unmixed type MutLncs in each cancer type. The darker color indicates a greater number of MutLncs in this group. (B) Bar plots represent the number of upregulated and downregulated MutLncs in KICH, LIHC, and STAD. The Venn diagrams show the MutLncs shared among the methylation, gene, TF, and microRNA effect process. GO terms enriched for different types of MutLncs ranked by −log10(P) are shown as bar plots. Methylation-, microRNA-, TF-, and gene-related MutLncs are presented in red, orange, blue, and green, respectively. (C) Two MutLncs simultaneously affected in different mixed effect groups in KICH. (D) Bar plots showing the number of cancer types containing MutLncs. Red, orange, green, and blue represent methylation, microRNA, TF, and gene-related mixed MutLncs, respectively.