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. 2018 Oct 15;25(4):344–358. doi: 10.1177/1073858418805002

Figure 1.

Figure 1.

Interictal spikes. (A) Three main types of activity observed in a human electroencephalography (EEG) recording. (a, b) Intracranial EEG traces showing interictal discharges (IID, blue), pre-ictal discharges (PID, pink) and ictal activity (yellow). (c) Amplitude distribution of IID and PID. (d) Spatial localization of each recording electrode and associated activity, showing a core of ictal activity (yellow spots) surrounded by IIDs (blue spots). Modified from Huberfeld and others (2011). (B) In vivo and in vitro recordings of interictal spikes in human mesial temporal lobe. Modified from Cohen and others (2002). (C) In vivo electrocorticogram (ECoG) recording of interictal spikes in a pilocarpine neocortical focal epilepsy mouse model (unpublished data). (D) In vitro local field potential (LFP) recording of interictal spikes in hippocampal slices superfused with high K+ solutions. Modified from Dzhala and Staley (2003).