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. Author manuscript; available in PMC: 2019 Sep 16.
Published in final edited form as: Curr Pharm Des. 2017 Nov 16;23(29):4226–4246. doi: 10.2174/1381612823666170616082125

Table 3.

Small molecular inhibitors targeting IGF-1R

Inhibitor Target Types of cancer
OSI-906 (Linsitinib) [63] TK/ATP-competitive NSCLC
BMS-754807 [64, 65] TK/ATP-competitive Colorectal cancer, rhabdomyosarcoma, neuroblastoma, osteosarcoma, Ewing sarcoma, and Wilms tumor
BVP-51004 [66] Not ATP-competitive Multiple myeloma