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Targeted therapy for Src
| Inhibitor | Target | Types of cancer |
|---|---|---|
| BMS-354825 (Dasatinib) [67–72] | Src Bcr-Abl PDGFR c-Kit EphA2 |
HR/HER2-positive breast cancer, triple-negative breast cancer, castration-resistant prostate cancer, NSCLC, colon cancer, HNSCC metastatic breast cancer, myeloid leukemia |
| AZD0530 (Saracatinib) [73] | Src Bcr-Abl |
castration-resistant prostate cancer |
| SKI-606 (Bosutinib) [74–78] | Src Bcr-Abl |
Myeloid leukemia, metastatic breast cancer |
