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PTPs involved in the regulation of STAT3 signaling in carcinogenesis.
| PTP | Target | Types of cancer |
|---|---|---|
| PTPRT [243, 246] | STAT3 | Colon cancer, head and neck cancer |
| TC-PTP [261, 284] | EGFR, STAT3, JAK1, JAK3, Src | Breast cancer, skin cancer |
| PTPRD [252] | STAT3 | Glioblastoma |
| SHP1 [267–270] | EGFR, JAK2, STAT3 | Lymphoma, liver cancer, breast cancer, colon cancer |
| SHP2 [272] | EGFR, JAK2, STAT3 | Liver cancer |
