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. 2019 Aug 6;8(12):5687–5701. doi: 10.1002/cam4.2454

Figure 2.

Figure 2

MiR‐20a‐5p promoted migration and invasion in MDA‐MB‐231 cells. A, The relative expression levels of miR‐20a‐5p in MDA‐MB‐231 cells transfected with miR‐20a‐5p mimics or miRNA negative control (miR‐NC). B, Transwell assay showed overexpression of miR‐20a‐5p promoted migratory and invasive abilities of MDA‐MB‐231 cells. C and D, The expression levels of MMP‐2, MMP‐9, and TIMP‐3 in MDA‐MB‐231 cells transfected with miR‐20a‐5p mimics or miRNA negative control (miR‐NC) were detected by qRT‐PCR and Western blot. E, The relative expression levels of miR‐20a‐5p in MDA‐MB‐231 cells transfected with miR‐20a‐5p inhibitor or negative control inhibitor (NC‐inhibitor). F, Transwell assay showed inhibition of miR‐20a‐5p suppressed migratory and invasive abilities of MDA‐MB‐231 cells. G and H, The expression levels of MMP‐2, MMP‐9, and TIMP‐3 in MDA‐MB‐231 cells transfected with miR‐20a‐5p inhibitor or negative control inhibitor (NC‐inhibitor) were detected by qRT‐PCR and Western blot. The data represent the mean ± SD from three independent experiments. **P < .01; ***P < .001. Student's t test