Table 1.
The incident cases and age‐standardized incidence of primary liver cancer in 1990 and 2017 and its temporal trends from 1990 to 2017
| Characteristics | 1990 | 2017 | 1990‐2017 | ||
|---|---|---|---|---|---|
|
Incident cases No. ×103 (95% UI) |
ASIR per 100 000 No. (95% UI) |
Incident cases No. ×103 (95% UI) |
ASIR per 100 000 No. (95% UI) |
EAPC in ASIR No. (95% CI) |
|
| Overall | 258.0 (240.2, 272.8) | 27.16 (25.31, 28.69) | 515.9 (486.2, 546.2) | 26.04 (24.57, 27.54) | −0.64 (−0.84, −0.44) |
| Sex | |||||
| Male | 182.7 (164.5, 196.7) | 37.70 (34.09, 40.59) | 395.2 (366.1, 426.8) | 40.19 (37.30, 43.37) | −0.23 (−0.06, −0.49) |
| Female | 75.3 (65.7, 83.6) | 16.39 (14.32, 18.25) | 120.7 (111.3, 132.3) | 12.19 (11.25, 13.36) | −1.47 (−1.30, −1.63) |
| Agea | |||||
| 15‐49 years | 87.3 (78.8, 93.9) | 13.06 (11.80, 14.05) | 106.8 (98.3, 116.1) | 14.35 (13.22, 15.61) | −0.85 (−1.39, −0.30) |
| 50‐69 years | 122.4 (114.5, 129.0) | 79.46 (74.34, 83.74) | 276.6 (258.6, 295.2) | 80.39 (75.16, 85.80) | −0.40 (−0.61, −0.18) |
| 70+ years | 47.1 (44.1, 50.3) | 121.76 (114.08,130.17) | 132.0 (124.4, 140.0) | 134.06 (126.33, 142.14) | 0.24 (0.09, 0.40) |
| Etiology | |||||
| Hepatitis B | 158.4 (146.6, 169.1) | 15.98 (14.79, 17.05) | 290.9 (270.9, 312.2) | 14.49 (13.53, 15.54) | −0.88 (−1.09, −0.67) |
| Hepatitis C | 43.8 (40.1, 47.3) | 5.14 (4.73, 5.52) | 103.1 (95.1, 111.8) | 5.34 (4.94, 5.77) | −0.22 (−0.39, −0.04) |
| Alcohol use | 18.6 (15.1, 23.0) | 2.02 (1.66, 2.47) | 43.3 (35.0, 53.9) | 2.16 (1.76, 2.66) | −0.27 (−0.50, −0.05) |
| NASH | 12.5 (11.0, 14.0) | 1.44 (1.27, 1.61) | 31.7 (27.9, 35.4) | 1.66 (1.46, 1.84) | 0.08 (−0.12, 0.29) |
| Other causes | 24.8 (21.5, 27.7) | 2.59 (2.28, 2.88) | 46.8 (41.7, 52.4) | 2.39 (2.14, 2.66) | −0.81 (−1.03, −0.59) |
Abbreviations: ASIR: age‐standardized incidence rate; CI: confidence interval; EAPC: estimated annual percentage change; NASH: nonalcoholic steatohepatitis; UI: uncertainty interval.
a
Crude mortality rate in each age group.