Table 2.
The number of deaths and age‐standardized mortality rates of primary liver cancer in 1990 and 2017 and the temporal trends from 1990 to 2017
| Characteristics | 1990 | 2017 | 1990‐2017 | ||
|---|---|---|---|---|---|
|
Deaths No. ×103 (95% UI) |
ASMR per 100 000 No. (95% UI) |
Deaths No. ×103 (95% UI) |
ASMR per 100 000 No. (95% UI) |
EAPC in ASMR No. (95% CI) |
|
| Overall | 245.3 (228.3, 258.9) | 26.72 (24.93, 28.19) | 418.2 (396.4, 441.2) | 21.30 (20.21, 22.44) | −1.16 (−1.35, −0.97) |
| Sex | |||||
| Male | 170.9 (154.5, 184.1) | 36.74 (33.25, 39.60) | 308.3 (288.5, 331.0) | 31.80 (29.80, 34.12) | −0.90 (−1.11, −0.70) |
| Female | 74.4 (65.0, 82.9) | 16.65 (14.59, 18.63) | 109.9 (102.2, 119.9) | 11.15 (10.38, 12.16) | −1.67 (−1.83, −1.52) |
| Agea | |||||
| 15‐49 years | 70.6 (63.8, 75.7) | 10.56 (9.55, 11.34) | 65.5 (61.1, 70.1) | 8.80 (8.21, 9.42) | −1.69 (−2.20, −1.19) |
| 50‐69 years | 118.9 (111.1, 125.2) | 77.19 (71.10, 81.27) | 219.1 (206.7, 232.6) | 63.69 (60.08, 67.61) | −0.99 (−1.20, −0.78) |
| 70+ years | 54.8 (51.4, 58.6) | 141.72 (132.95, 151.65) | 133.3 (127.1, 140.7) | 135.34 (129.08, 142.86) | −0.28 (−0.52, −0.03) |
| Etiology | |||||
| Hepatitis B | 146.5 (135.4, 156.1) | 15.20 (14.10, 16.18) | 226.4 (211.9, 241.5) | 11.31 (10.59, 12.03) | −1.56 (−2.94, −0.16) |
| Hepatitis C | 44.7 (41.0, 48.1) | 5.44 (5.03, 5.86) | 90.3 (83.6, 97.8) | 4.77 (4.43, 5.15) | −0.79 (−1.37, −0.21) |
| Alcohol use | 18.3 (15.0, 22.5) | 1.53 (1.25, 1.88) | 35.8 (29.2, 44.4) | 1.81 (1.49, 2.23) | −0.98 (−2.35, 0.41) |
| NASH | 12.5 (11.0, 14.1) | 1.50 (1.33, 1.70) | 27.6 (24.4, 30.8) | 1.47 (1.30, 1.63) | −0.44 (−1.06, 0.18) |
| Other causes | 23.3 (20.4, 25.9) | 2.54 (2.23, 2.81) | 37.9 (34.1, 42.3) | 1.95 (1.76, 2.16) | −1.35 (−1.76, −0.95) |
Abbreviations: ASIR: age‐standardized incidence rate; CI: confidence interval; EAPC: estimated annual percentage change; NASH: nonalcoholic steatohepatitis; UI: uncertainty interval.
a
Crude mortality rate in each age group.