Table 3.
Positive detection rates of ColoDefense test for CRC of different ages, genders, tumor locations, and tumor sizes
| Methylated SDC2 (%) | P‐value | Methylated SEPT9 (%) | P‐value | ColoDefense (%) | P‐value | |
|---|---|---|---|---|---|---|
| Age | ||||||
| <60 (n = 46) | 29 (63.0) | .318 | 38 (82.6) | .899 | 41 (89.1) | .947 |
| ≥60 (n = 71) | 51 (71.8) | 58 (81.7) | 63 (88.7) | |||
| Gender | ||||||
| Male (n = 64) | 45 (70.3) | .621 | 55 (85.9) | .229 | 58 (90.6) | .511 |
| Female (n = 53) | 35 (66.0) | 41 (77.4) | 46 (86.8) | |||
| Location | ||||||
| Proximal (n = 61) | 43 (70.5) | .471 | 49 (80.3) | .522 | 53 (86.9) | .537 |
| Distal (n = 53) | 34 (64.2) | 45 (84.9) | 48 (90.6) | |||
| N/A (n = 3) | 3 (100.0) | 2 (66.7) | 3 (100.0) | |||
| Size | ||||||
| <3 cm (n = 9) | 3 (33.3) | .021a | 5 (55.6) | .088a | 6 (66.7) | .076a |
| 3‐6 cm (n = 77) | 55 (71.4) | .956b | 62 (80.5) | .064b | 68 (88.3) | .261b |
| >6 cm (n = 25) | 18 (72.0) | .041c | 24 (96.0) | .003c | 24 (96.0) | .019c |
| N/A (n = 6) | 4 (66.7) | 5 (83.3) | 6 (100.0) | |||
Abbreviations: CRC, colorectal cancer; N/A, not applicable.
a
P‐value between <3 cm and 3‐6 cm.
b
P‐value between 3‐6 cm and >6 cm.
c
P‐value between <3 cm and >6 cm.