Figure 5.

LSD1 inhibition increases global histone 3 K4 and histone 3 K9 methylation levels in bone marrow cells. (A) Western blot showing protein levels of histone 3 lysine 4 trimethylation (top), histone 3 lysine 9 dimethylation (middle), and total histone 3 (bottom, loading control). (B) Quantification of histone 3 lysine 4 trimethylated and (left) and histone 3 lysine 9 dimethylated protein. n = 3 in triplicate. Statistical analysis was conducted using Student t tests with Welch correction. ^∗P < 0.05 and ^∗∗P < 0.01.