Figure 1.

Panels A and B show a chest computed tomography from the patient before (A) and after (B) ARI-0001 infusion. Yellow arrows point to bilateral axillary lymphadenopathy remarkably improving upon therapy. Panels C and D show flow cytometry plots from bone marrow aspirates before (C) and after (D) ARI-0001 infusion. CLL cells are depicted in blue while normal T and NK-cells are depicted in green and yellow, respectively. Notice that the patient had received the anti-CD20 monoclonal antibody obinutuzumab right before study inclusion, thus explaining the lack of normal (CD19⁺/CD5⁻) B cells even before ARI-0001 infusion. CLL = chronic lymphocytic leukemia.