Table 2.
Metric | N | Mean (SD)a | Median (IQRb)c | ||
Total Index score | |||||
|
Baseline to week 24 change | 72 | −1.4 (8.1) | 0 (10) | |
|
Baseline to week 52 change | 66 | 5.8 (7.4)d | 6 (11)d | |
|
Week 24 to week 52 change | 64 | 6.8 (6.3)d | 6 (8)d | |
Immediate memory | |||||
|
Baseline to week 24 change | 72 | −3.7 (12.7)f | −3.5 (14.5)e | |
|
Baseline to week 52 change | 66 | 7.8 (11.4)d | 8 (15)d | |
|
Week 24 to week 52 change | 64 | 12.2 (11.3)d | 12 (17)d | |
Visuospatial | |||||
|
Baseline to week 24 change | 72 | −0.5 (14.9) | 0 (21.5) | |
|
Baseline to week 52 change | 66 | 0.5 (13.7) | 0 (22) | |
|
Week 24 to week 52 change | 64 | 0.3 (11.1) | 0 (16) | |
Language | |||||
|
Baseline to week 24 change | 72 | 0.9 (11.0) | 2 (11.5) | |
|
Baseline to week 52 change | 66 | 5.7 (12.5)d | 5.5 (15)d | |
|
Week 24 to week 52 change | 64 | 4.5 (9.7)d | 5 (11.5)d | |
Attention | |||||
|
Baseline to week 24 change | 72 | −1.5 (12.1) | −3 (13) | |
|
Baseline to week 52 change | 66 | 2.0 (12.6) | 0 (16) | |
|
Week 24 to week 52 change | 64 | 3.5 (9.7)e | 3 (13)e | |
Delayed memory | |||||
|
Baseline to week 24 change | 72 | 0.9 (10.5) | 0 (9.5) | |
|
Baseline to week 52 change | 66 | 5.4 (12.5)d | 4 (14)d | |
|
Week 24 to week 52 change | 64 | 3.6 (9.0)e | 4 (7)d |
aP values in the mean column are calculated using 2-sided paired t tests to compare means at the 2 time points.
bIQR: interquartile range.
cP values in the median column are calculated using 2-sided nonparametric signed-rank tests to compare distributions at the 2 time points.
dP<.001.
eP<.01.
fP=.02.