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Reduction of Dock1 and upregulation of miR-486-5p reduced IL-22- induced breast cancer cell invasion in vivo. A. Comparison of lung metastasis between groups. B. Lung metastatic nodules were calculated and plotted (n=10). C. Expression of Dock1, Snail, E-cadherin, and Vimentin was determined in mice xenograft tumors by use of western blot. Used β-actin as a loading control. Quantifications of relative protein levels are shown below the blots.
