TABLE 1.
Characterization of Pre-treatment and Post-treatment N. gonorrhoeae Isolates From the Index Patient
| Isolate | mtrR Promoter Region Mutations | Amino Acid Changes in Coding Region of MtrR | 23S rRNA* | |||
|---|---|---|---|---|---|---|
| Allele 1 | Allele 2 | Allele 3 | Allele 4 | |||
| Pre-treatment P1101 | Deletion of A | No mutation | C2599T mutation | No mutation | No mutation | C2599T mutation |
| Post-treatment P1102 | Deletion of A | H105Y mutation | C2599T mutation | C2599T mutation | C2599T mutation | C2599T mutation |
| Susceptible control strain SC113 | No mutation | No mutation | No mutation | No mutation | No mutation | No mutation |
*
23S rRNA N. gonorrhoeae numbering.
A indicates adenine; C, cytosine; T, thymine; H, histidine; Y, tyrosine.