Table 1:
Characteristics | Not dialyzed within 24 hours of loop diuretic challenge (N=525) | Dialyzed within 24 hours of loop diuretic challenge (N=162) | p value | |
---|---|---|---|---|
Age | 67.6 ± 15.6 | 63.9 ± 14.5 | .008 | |
Sex (Male) (%) | 49.1 | 56.2 | .1 | |
Charlson’s Score | 5.8±2.7 | 4.9±2.4 | <.001 | |
SOFA score* | 8.3±3.4 | 10.4±3.9 | <.001 | |
Highest serum potassium*(meq/L) | 4.5±0.8 | 4.8±0.9 | <.001 | |
Lowest serum bicarbonate* (mmol/L) | 19.3±4.9 | 18.4±4.8 | .06 | |
Baseline average urine output (ml) | 20.7 (7.5–46.3) | 10.1(3.9–18.8) | <.001 | |
Baseline serum albumin (mg/dL) | 2.9±0.6 | 2.9±0.6 | .8 | |
Baseline serum creatinine (mg/dL) | 1.0 (0.8–1.3) | 0.9 (0.7–1.2) | .05 | |
Baseline estimated glomerular filtration rate (ml/min) | 59 (47–94) | 69(50–99) | .04 | |
Serum creatinine* (mg/dL) | 3.5 (2.5–4.5) | 4.1 (3.0–5.3) | <.001 | |
Blood Urea Nitrogen* (mg/dL) | 59 (41–78) | 63 (45–84) | .04 | |
Serum pH* | 7.35±0.08 | 7.32±0.11 | .007 | |
Race | Caucasian | 87.8 | 88.8 | .9 |
African American | 1.9 | 2.5 | ||
Asian | 1.1 | 1.2 | ||
Others | 3.1 | 1.9 | ||
Unknown | 6.1 | 5.6 | ||
Mechanical Ventilation Use | 52.2 | 52.3 | .1 |
On the day of the loop diuretic challenge