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. 2019 Sep 16;2019(9):CD013120. doi: 10.1002/14651858.CD013120.pub2

1. Characteristics and potential effect modifiers of included studies ordered by comparison.

Study name Intervention 1 Intervention 2 Intervention 1: number of participants Intervention 2: number of participants Presence of other features of decompensation (hepatorenal syndrome, hepatic encephalopathy, or variceal bleeding) Alcohol‐related cirrhosis Viral‐related cirrhosis Other causes for cirrhosis Treated for ascites in addition to antibiotics (e.g. albumin or diuretics) Follow‐up in months Year of recruitment
Abd‐Elsalam 2016 Cefotaxime Ceftriaxone Not stated Not stated Not stated Not stated Not stated Not stated Not stated 0.25 2014
Tuncer 2003 Cefotaxime Ceftriaxone 18 19 Includes people with and without other features of decompensation Not stated Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 0.25 Not stated
Yim 2017 Cefotaxime Ceftriaxone Not stated Not stated Not stated Not stated Not stated Not stated Not stated 0.25 2007‐2016
Ahmed Ather Ch 2014 Ciprofloxacin Ceftriaxone 120 120 Not stated Not stated Not stated Not stated Not stated 0.25 2011
Tuncer 2003 Ciprofloxacin Ceftriaxone 16 19 Includes people with and without other features of decompensation Not stated Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 0.25 Not stated
Yim 2017 Ciprofloxacin Ceftriaxone Not stated Not stated Not stated Not stated Not stated Not stated Not stated 0.25 2007‐2016
Figueiredo 1997 Cefixime Ceftriaxone 20 18 Includes people with and without other features of decompensation Includes people with and without alcohol‐related cirrhosis Not stated Not stated Not stated 0.25 Not stated
Gomez‐Jimenez 1993 Cefonicid Ceftriaxone 30 30 Not stated Includes people with and without alcohol‐related cirrhosis Not stated Includes people with and without other causes of cirrhosis Not stated 0.5 1987‐1990
Tuncer 2003 Ciprofloxacin Cefotaxime 16 18 Includes people with and without other features of decompensation Not stated Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 0.25 Not stated
Yim 2017 Ciprofloxacin Cefotaxime Not stated Not stated Not stated Not stated Not stated Not stated Not stated 0.25 2007‐2016
Chen 2005 Amikacin Cefotaxime 18 19 Not stated Includes people with and without alcohol‐related cirrhosis Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 1 2000‐2002
Navasa 1996 Ofloxacin Cefotaxime 64 59 Includes people with and without other features of decompensation Includes people with and without alcohol‐related cirrhosis Not stated Includes people with and without other causes of cirrhosis Not stated 0.5 1992‐1994
Angeli 2006 Ceftazidime Ciprofloxacin 55 61 Not stated Includes people with and without alcohol‐related cirrhosis Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Includes people receiving and not receiving other treatments for ascites 3 Not stated
Piano 2016 Meropenem plus daptomycin Ceftazidime 15 16 Not stated Includes people with and without alcohol‐related cirrhosis Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 3 2011 to 2014
Rastegar 1998 Pefloxacin Ampicillin plus gentamycin 11 9 Not stated Not stated Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 0.25 Not stated
Jindal 2016 Imipenem Cefepime 87 88 Includes people with and without other features of decompensation Includes people with and without alcohol‐related cirrhosis Includes people with and without viral‐related cirrhosis Includes people with and without other causes of cirrhosis Not stated 3 2012‐2014