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CCM lesion burden in a non-sensitized murine model after B cell depletion. Anti-BR3 antibody treatment of Pdcd10+/− mice significantly decreased the amount of mature stage 2 lesions, but did not affect the number of stage 1 pre-lesions, compared to untreated mice run contemporaneously. Horizontal lines indicate the mean (longer lines) and standard error of the mean (shorter lines)
