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. 2019 Sep 10;8(1):1324–1336. doi: 10.1080/22221751.2019.1663131

Figure 2.

Figure 2.

Lung titers and morbidity in H7 SGR and SPM virus infected mice. BALB/c mice were inoculated intranasally with 105 p.f.u. SC35-HASC35F (filled diamond), SC35-HA111T (triangle, half filled), SC35-HA146S (upside down triangle, half filled) and SC35-HA340R (filled upside down triangle). (A) From each group (n = 3) mice were sacrificed on 3 and 6 d p.i., lungs were harvested and viral titers of the lung homogenates were determined via plaque assay on MDCK cells. SC35-HASC35F (black), SC35-HA111T (bright grey), SC35-HA146S (grey) and SC35-HA340R (dark grey). (B) Weight loss of PBS mock infected mice (n = 19), of SC35 (n = 5), SC35-HASC35F (n = 14), SC35-HAI111T (n = 11), SC35-HAA146S (n = 11) and SC35-HAG340R (n = 15) infected BALB/c mice was recorded for 14 days and plotted as percentages of the original weight from day 0. (C) Survival of the in (A) shown BALB/c mice was recorded for 14 days and depicted in a survival graph.