Table 3.
Percentage malaria parasitaemia, chemosuppression, and percentage inhibition in P. berghei passaged mice.
| Groups | Day 0 MP (%) | Day 3 MP (%) | Day 3 chemosuppression (%) | Day 3 percentage inhibition |
|---|---|---|---|---|
| Group 1 | 0.00 ± 0.00aA | 0.00 ± 0.00aA | – | – |
| Group 2 | 45.75 ± 8.18bA | 86.50 ± 5.0eB | – | – |
| Group 3 | 42.50 ± 6.45bB | 1.15 ± 0.15dA | 98.67 ± 9.72a | 97.29 ± 9.77a |
| Group 4 | 48.25 ± 6.34bB | 15.25 ± 2.50cA | 82.37 ± 5.05c | 68.39 ± 6.07d |
| Group 5 | 49.50 ± 4.20bB | 8.00 ± 2.16bcA | 90.75 ± 5.68b | 84.84 ± 4.86c |
| Group 6 | 47.75 ± 3.86bB | 3.50 ± 1.00bA | 95.95 ± 8.05a | 92.67 ± 7.41b |
Results are expressed in means ± SD (n = 5); Mean values with different lowercase letters within a column and mean values with uppercase letters as superscripts across a row are considered significant at p < 0.05.
Group 1 = Normal control (normal saline).
Group 2 = Parasite control (malaria-passaged untreated).
Group 3 = Standard control (malaria-passaged and treated with 140 mg/kg b.w of combisunate).
Group 4 = Malaria-passaged and treated with 200 mg/kg b.w. of the extract.
Group 5 = Malaria-passaged and treated with 400 mg/kg b.w. of the extract.
Group 6 = Malaria-passaged and treated with 600 mg/kg b.w. of the extract.
Note: The alphabets in superscript are statistical codes signifying the statistical relationships between two variables. Same alphabet as superscript means that there was no statistical difference between the body weights before and after extract administration.