Table 2.
Rank | Radiomic feature | Mean value in treatment effect (standard error) |
Mean value in true progression (standard error) |
P value* | AUC† |
---|---|---|---|---|---|
1 | T1c minimum | 190.63 (17.12) | 139.42 (17.71) | .04 | 0.70 |
2 | FLAIR NGTDM coarseness | 0.05 (0.01) | 0.03 (0.00) | .03 | 0.69 |
3 | T1c NGTDM texture strength | 116.30 (13.68) | 82.34 (9.49) | .05 | 0.68 |
4 | FLAIR kurtosis | 3.09 (0.26) | 3.53 (0.15) | .15 | 0.67 |
5 | T1c NGTDM coarseness | 0.04 (0.00) | 0.03 (0.00) | .04 | 0.65 |
6 | T1c GLRLM gray level nonuniformity | 594.39 (70.12) | 842.25 (75.11) | .02 | 0.65 |
7 | T1c fractal dimension | 1.37 (0.03) | 1.43 (0.02) | .08 | 0.65 |
8 | FLAIR minimum | 4107.00 (353.47) | 3130.63 (337.94) | .05 | 0.65 |
9 | T1c GLRLM run percentage | 0.41 (0.03) | 0.48 (0.02) | .04 | 0.63 |
10 | FLAIR NGTDM texture strength | 338.99 (93.26) | 203.51 (31.36) | .18 | 0.63 |
Abbreviations: FLAIR = fluid-attenuated inversion recovery; GLRLM = gray level run-length matrix; NGTDM = neighborhood gray tone difference matrix; T1c = T1 post contrast.
P value is for difference in the means according to unpaired Student’s t test.
AUC is area under the receiver operating characteristic curve for performance of the radiomic feature on univariate logistic regression.