Table 3. Performance of Xpert MTB/RIF and non-molecular methods against composite culture for the diagnosis of presumptive TBLN patients.
Laboratory methods | Sensitivity (95%CI) | Specificity (95%CI) | PPV (95%CI) | NPV (95%CI) |
---|---|---|---|---|
Cytology | 94.1%(91.5–96.5) | 53.6%(48.4–58.8) | 62.1%(57.1–67.1) | 91.8%(89–94.6) |
Xpert MTB/RIF | 78%(73.7–82.3) | 74%(69.4–78.6) | 71%(66.3–75.7) | 81%(76.9–85.1) |
ZN | 30.9%(26–35.7) | 98.8%(97.8–99.8) | 95.5%(93.5–97.5) | 63.8%(58.8–68.8) |
FM | 47%(941.8–52.2) | 94%(91.5–96.5) | 86.5%(83–90) | 68.7%(63.9–73.5) |