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. 2019 Sep 16;14(9):e0219561. doi: 10.1371/journal.pone.0219561

Table 2. Wound healing processes and healing phases of the animals administered different treatments on day 7.

Groups Wound healing processes Healing phases
S U RE FP CD IC I P R
I +++ +++ - ++ ++ +++ +++ +++ -
II ++ + + +/++ ++ ++ ++ ++/+++ ++
III +++ ++/+++ -/+ ++ ++ ++/+++ ++ +++ -
IV ++ + -/+ + + ++ + ++ +
V ++ ++ -/+ ++ ++ ++ +/++ ++ +
VI ++ + + + ++ ++ ++ +++ ++

HE (Hematoxylin &Eosin) stained sections were scored as mild (+), moderate (++) and severe (+++) for epidermal and/or dermal re-modeling. S: Scab, U: Ulcus, RE: Re-epithelization, FP:Fibroblast proliferation, CD: Collagen depositions, IC: Inflammatory cells infiltration, I: Inflammation phase, P: Proliferation phase, R: Re-modeling phase.