Table 3. Wound healing processes and healing phases of the animals administered different treatments on day 14.
Groups | Wound healing processes | Healing phases | |||||||
---|---|---|---|---|---|---|---|---|---|
S | U | RE | FP | CD | IC | I | P | R | |
I | ++ | ++ | -/+ | ++ | ++ | ++ | ++ | +++ | -/+ |
II | + | - | +++ | +/++ | ++ | + | + | ++ | +++ |
III | ++ | ++/+++ | + | ++ | ++ | ++ | ++ | ++/+++ | + |
IV | ++ | + | ++ | ++ | + | +/++ | + | +/++ | ++ |
V | ++ | ++ | -/+ | ++ | ++ | +/++ | +/++ | ++ | +/++ |
VI | + | -/+ | +++ | ++ | ++ | -/+ | -/+ | ++ | +++ |
HE (Hematoxylin &Eosin) stained sections were scored as mild (+), moderate (++) and severe (+++) for epidermal and/or dermal re-modeling. S: Scab, U: Ulcus, RE: Re-epithelization, FP:Fibroblast proliferation, CD: Collagen depositions, IC: Inflammatory cells infiltration, I: Inflammation phase, P: Proliferation phase, R: Re-modeling phase.