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. 2019 Sep 16;14(9):e0219561. doi: 10.1371/journal.pone.0219561

Table 3. Wound healing processes and healing phases of the animals administered different treatments on day 14.

Groups Wound healing processes Healing phases
S U RE FP CD IC I P R
I ++ ++ -/+ ++ ++ ++ ++ +++ -/+
II + - +++ +/++ ++ + + ++ +++
III ++ ++/+++ + ++ ++ ++ ++ ++/+++ +
IV ++ + ++ ++ + +/++ + +/++ ++
V ++ ++ -/+ ++ ++ +/++ +/++ ++ +/++
VI + -/+ +++ ++ ++ -/+ -/+ ++ +++

HE (Hematoxylin &Eosin) stained sections were scored as mild (+), moderate (++) and severe (+++) for epidermal and/or dermal re-modeling. S: Scab, U: Ulcus, RE: Re-epithelization, FP:Fibroblast proliferation, CD: Collagen depositions, IC: Inflammatory cells infiltration, I: Inflammation phase, P: Proliferation phase, R: Re-modeling phase.