Table 2. Results of the gene-level association tests.
Chr | Gene | Start | Stop | P-values | |||
---|---|---|---|---|---|---|---|
AQt | H | Q | QF | ||||
2 | DHRS9 | 169,629,544 | 169,660,923 | 0.007 | 0.018 | 0.005 | 0.009 |
6 | ESR1 | 152,053,323 | 152,466,101 | 0.04 | 0.046 | 0.048 | 0.047 |
12 | RARG | 51,890,619 | 51,912,303 | 0.012 | 0.318 | 0.022 | 0.056 |
1 | H3F3A | 224,317,043 | 224,326,326 | 0.037 | 0.594 | 0.094 | 0.166 |
5 | SRD5A1 | 6,686,499 | 6,722,675 | 0.04 | 0.135 | 0.063 | 0.219 |
1 | HDAC1 | 32,530,294 | 32,571,811 | 0.029 | 0.106 | 0.096 | 0.357 |
AQt, All Quantitative association test; H, Half case-control association test; Q, Quartile case-control association test; QF, Quartile Fisher’s exact test.
This table shows genes significantly associated with response to dutasteride (p <0.05). This test was performed using VEGAS, with start-stop positions in hg18.