Table 3.

Grade 2 and above AEs at least possibly related to neratinib (N = 16)

AE	Grade 2, N (%)	Grade 3, N (%)	Total, N (%)
Diarrhea	7 (44%)	4 (25%)*	11 (69%)
Anorexia	7 (44%)	0	7 (44%)
Fatigue	4 (25%)	1 (6%)	5 (31%)
Anemia	3 (19%)	0	3 (19%)
Nausea	3 (19%)	0	3 (19%)
Dehydration	1 (6%)	1 (6%)	2 (13%)
Dyspepsia	2 (13%)	0	2 (13%)
Hypophosphatemia	2 (13%)	0	2 (13%)
Vomiting	2 (13%)	0	2 (13%)
Syncope	0	1 (6%)	1 (6%)

NOTE: AEs that are grade 2 or above experienced by more than one patient or any occurrence of grade 3 AEs are included.